N
Centralnervesystemet
Epilepsi
Epilepsi hos voksne
Epilepsi hos børn
Feberkramper hos børn
Akutte anfald og status epilepticus
Antiepileptika
Barbitursyrederivater (epilepsi)
Benzodiazepiner (epilepsi)
Brivaracetam
Cannabinoider (Epilepsi)
Carbamazepin
Cenobamat
Eslicarbazepin
Fenfluramin
Gabapentin
Lacosamid
Lamotrigin
Levetiracetam
Oxcarbazepin
Perampanel
Phenytoin og fosphenytoin
Pregabalin (epilepsi)
Rufinamid
Stiripentol
Succinimidderivater
Topiramat (epilepsi)
Valproat (epilepsi)
Vigabatrin
Zonisamid
Lamotrigin
N03AX
Revideret: 14.12.2021
Jakob Christensen (Forfatter),
Dansk Neurologisk Selskab
Helle Hjalgrim (Referent),
Dansk Epilepsi Selskab
Indledning | Anvendelsesområder | Behandlingsvejledning | Præparatvalg | Doseringsforslag | Nedsat lever- og/eller nyrefunktion | Kontraindikationer | Forsigtighedsregler | Patientsikkerhed | Bivirkninger | Interaktioner | Graviditet | Amning | Forgiftning | Farmakodynamik | Farmakokinetik | Tilskud | Præparater | Referencer
Lamotrigin forlænger refraktærperioden for de spændingsafhængige natriumkanaler, men har også en effekt på høj spændingsaktiverede calciumkanaler.
Anvendelsesområder
- Alle typer epileptiske anfald inklusiv supplerende behandling ved Lennox-Gastaut syndrom. Effekten over for myoklonier er dog beskeden, og forværring af disse kan ses.
- Forebyggelse af depressive episoder ved bipolar lidelse.
Forgiftning
- Klinik: Primære effekter på CNS, somnolens, nystagmus, ataksi, koma og kramper. Hypokaliæmi, overledningsforstyrrelser (QRS-forlængelse) og gastro-intestinale manifestationer er beskrevet.
- Behandling: Aktivt kul og symptomatisk behandling. Monitorering af EKG ved alvorlig overdosis.
Ved tvivlsspørgsmål: Ring til Giftlinjen.
Præparater
| Indholdsstof | Navn og firma | Dispform og styrke | Pakning | Pris enh. | Pris DDD |
|---|---|---|---|---|---|
| Lamotrigin | Lamictal® GSK Pharma
|
tabletter 25 mg | 56 stk. (blister) | 3,93 | 47,17 |
| Lamotrigin | Lamictal® GSK Pharma
|
tabletter 50 mg | 56 stk. (blister) | 6,49 | 38,92 |
| Lamotrigin | Lamictal® GSK Pharma
|
tabletter 100 mg | 56 stk. (blister) | 11,35 | 34,05 |
| Lamotrigin | Lamictal® GSK Pharma
|
tabletter 100 mg | 56 stk. (blister) | 9,38 | 28,14 |
| Lamotrigin | Lamictal® GSK Pharma
|
tabletter 100 mg | 98 stk. (blister) | 8,14 | 24,41 |
| Lamotrigin | Lamictal® GSK Pharma
|
tabletter 200 mg | 56 stk. (blister) | 18,25 | 27,37 |
| Lamotrigin | Lamictal® GSK Pharma
|
Tygge-/dispergibel tablet 2 mg | 30 stk. | 2,51 | 375,75 |
| Lamotrigin | Lamictal® GSK Pharma
|
Tygge-/dispergibel tablet 5 mg | 60 stk. | 2,22 | 133,30 |
| Lamotrigin | Lamictal® GSK Pharma
|
Tygge-/dispergibel tablet 25 mg | 56 stk. (blister) | 3,81 | 45,70 |
| Lamotrigin | Lamictal® GSK Pharma
|
Tygge-/dispergibel tablet 25 mg | 56 stk. (blister) | 2,22 | 26,58 |
| Lamotrigin | Lamictal® GSK Pharma
|
Tygge-/dispergibel tablet 50 mg | 56 stk. (blister) | 6,33 | 37,97 |
| Lamotrigin | Lamictal® GSK Pharma
|
Tygge-/dispergibel tablet 100 mg | 56 stk. (blister) | 11,35 | 34,05 |
| Lamotrigin | Lamictal® GSK Pharma
|
Tygge-/dispergibel tablet 200 mg | 56 stk. (blister) | 18,96 | 28,44 |
| Lamotrigin | Lamoprim Parallelimport
|
dispergible tabletter 50 mg | 60 stk. (blister) | 2,45 | 14,68 |
| Lamotrigin | Lamoprim Parallelimport
|
dispergible tabletter 50 mg | 100 stk. (blister) | 3,12 | 18,70 |
| Lamotrigin | Lamoprim Parallelimport
|
dispergible tabletter 100 mg | 60 stk. (blister) | 3,74 | 11,23 |
| Lamotrigin | Lamoprim Parallelimport
|
dispergible tabletter 100 mg | 100 stk. (blister) | 2,67 | 8,02 |
| Lamotrigin | Lamoprim Parallelimport
|
dispergible tabletter 200 mg | 60 stk. (blister) | 3,01 | 4,51 |
| Lamotrigin | Lamoprim Parallelimport
|
dispergible tabletter 200 mg | 100 stk. (blister) | 3,32 | 4,98 |
| Lamotrigin | Lamotab Parallelimport
|
dispergible tabletter 100 mg | 56 stk. (blister) | 3,72 | 11,16 |
| Lamotrigin | Lamotab Parallelimport
|
dispergible tabletter 100 mg | 60 stk. (blister) | ||
| Lamotrigin | Lamotab Parallelimport
|
dispergible tabletter 100 mg | 100 stk. (blister) | 1,79 | 5,38 |
| Lamotrigin | Lamotab Parallelimport
|
dispergible tabletter 200 mg | 56 stk. (blister) | 1,89 | 2,84 |
| Lamotrigin | Lamotab Parallelimport
|
dispergible tabletter 200 mg | 112 stk. (blister) | 1,43 | 2,14 |
| Lamotrigin | Lamotrigin "1A Farma" 1A Farma
|
tabletter 25 mg | 60 stk. (blister) | 3,17 | 38,07 |
| Lamotrigin | Lamotrigin "1A Farma" 1A Farma
|
tabletter 50 mg | 60 stk. (blister) | 1,04 | 6,24 |
| Lamotrigin | Lamotrigin "1A Farma" 1A Farma
|
tabletter 100 mg | 60 stk. (blister) | 1,08 | 3,23 |
| Lamotrigin | Lamotrigin "1A Farma" 1A Farma
|
tabletter 200 mg | 60 stk. (blister) | 1,00 | 1,50 |
| Lamotrigin | Lamotrigin "1A Pharma" Parallelimport
Udgået
23.01.2023
|
tabletter 200 mg | 100 stk. (blister) | ||
| Lamotrigin | Lamotrigin "Aristo" Aristo Pharma Nordic
|
tabletter 50 mg | 56 stk. (blister) | ||
| Lamotrigin | Lamotrigin "Aristo" Aristo Pharma Nordic
|
tabletter 200 mg | 56 stk. (blister) | 1,45 | 2,17 |
| Lamotrigin | Lamotrigin "Aurobindo" Orion Pharma
|
tabletter 25 mg | 56 stk. (blister) | ||
| Lamotrigin | Lamotrigin "Aurobindo" Orion Pharma
|
tabletter 25 mg | 100 stk. | ||
| Lamotrigin | Lamotrigin "Aurobindo" Orion Pharma
|
tabletter 50 mg | 56 stk. (blister) | 1,15 | 6,90 |
| Lamotrigin | Lamotrigin "Aurobindo" Orion Pharma
|
tabletter 100 mg | 56 stk. (blister) | 0,90 | 2,70 |
| Lamotrigin | Lamotrigin "Aurobindo" Orion Pharma
|
tabletter 100 mg | 100 stk. | ||
| Lamotrigin | Lamotrigin "Aurobindo" Orion Pharma
|
tabletter 200 mg | 56 stk. (blister) | ||
| Lamotrigin | Lamotrigin "Aurobindo" Orion Pharma
|
tabletter 200 mg | 100 stk. | ||
| Lamotrigin | Lamotrigin "Aurobindo" Orion Pharma
|
tabletter 200 mg | 100 stk. (blister) | ||
| Lamotrigin | Lamotrigin "Bluefish" Bluefish
|
tabletter 25 mg | 56 stk. (blister) | 1,02 | 12,22 |
| Lamotrigin | Lamotrigin "Bluefish" Bluefish
|
tabletter 50 mg | 56 stk. (blister) | 0,92 | 5,50 |
| Lamotrigin | Lamotrigin "Bluefish" Bluefish
|
tabletter 100 mg | 56 stk. (blister) | ||
| Lamotrigin | Lamotrigin "Bluefish" Bluefish
|
tabletter 200 mg | 56 stk. (blister) | 1,48 | 2,23 |
| Lamotrigin | Lamotrigin "Mylan" Viatris
|
tabletter 100 mg | 60 stk. (blister) | 0,87 | 2,62 |
| Lamotrigin | Lamotrigin "Mylan" Viatris
|
tabletter 200 mg | 60 stk. (blister) | 1,53 | 2,30 |
| Lamotrigin | Lamotrigin "Nordic Prime" Parallelimport
|
tabletter 25 mg | 100 stk. (blister) | 1,47 | 17,62 |
| Lamotrigin | Lamotrigin "Nordic Prime" Parallelimport
|
tabletter 50 mg | 60 stk. (blister) | 1,04 | 6,24 |
| Lamotrigin | Lamotrigin "Nordic Prime" Parallelimport
|
tabletter 50 mg | 100 stk. (blister) | 1,46 | 8,75 |
| Lamotrigin | Lamotrigin "Nordic Prime" Parallelimport
|
tabletter 100 mg | 60 stk. (blister) | ||
| Lamotrigin | Lamotrigin "Nordic Prime" Parallelimport
|
tabletter 100 mg | 100 stk. (blister) | 2,45 | 7,34 |
| Lamotrigin | Lamotrigin "Nordic Prime" Parallelimport
|
tabletter 200 mg | 60 stk. (blister) | 0,86 | 1,29 |
| Lamotrigin | Lamotrigin "Nordic Prime" Parallelimport
|
tabletter 200 mg | 100 stk. (blister) | 2,02 | 3,03 |
| Lamotrigin | Lamotrigin "Orifarm" Orifarm Generics
|
tabletter 50 mg | 56 stk. (blister) | 0,97 | 5,84 |
| Lamotrigin | Lamotrigin "Orifarm" Orifarm Generics
|
tabletter 100 mg | 56 stk. (blister) | 1,07 | 3,20 |
| Lamotrigin | Lamotrigin "Orifarm" Orifarm Generics
|
tabletter 200 mg | 56 stk. (blister) | 1,13 | 1,69 |
| Lamotrigin | Lamotrigin "Paranova" Parallelimport
Udgået
26.12.2022
|
tabletter 25 mg | 60 stk. (blister) | ||
| Lamotrigin | Lamotrigin "Stada" STADA Nordic
|
dispergible tabletter 5 mg | 60 stk. (blister) | 2,13 | 128,05 |
| Lamotrigin | Lamotrigin "Stada" STADA Nordic
|
dispergible tabletter 25 mg | 60 stk. (blister) | 2,96 | 35,53 |
| Lamotrigin | Lamotrigin "Stada" STADA Nordic
|
dispergible tabletter 50 mg | 60 stk. (blister) | 2,54 | 15,22 |
| Lamotrigin | Lamotrigin "Stada" STADA Nordic
|
dispergible tabletter 100 mg | 60 stk. (blister) | 3,63 | 10,89 |
| Lamotrigin | Lamotrigin "Stada" STADA Nordic
|
dispergible tabletter 100 mg | 100 stk. (blister) | 1,67 | 5,01 |
| Lamotrigin | Lamotrigin "Stada" STADA Nordic
|
dispergible tabletter 200 mg | 60 stk. (blister) | 1,75 | 2,63 |
| Lamotrigin | Lamotrigin "Stada" STADA Nordic
|
dispergible tabletter 200 mg | 100 stk. (blister) | 1,41 | 2,12 |
| Lamotrigin | Lamotrigin "Teva" TEVA
|
dispergible tabletter 25 mg | 50 stk. (blister) | 2,00 | 24,00 |
| Lamotrigin | Lamotrigin "Teva" TEVA
|
dispergible tabletter 50 mg | 50 stk. (blister) | 2,40 | 14,40 |
| Lamotrigin | Lamotrigin "Teva" TEVA
|
dispergible tabletter 200 mg | 50 stk. (blister) | 4,64 | 6,97 |
| Lamotrigin | Lamotrigin "Teva" TEVA
|
dispergible tabletter 200 mg | 100 stk. (blister) | 3,65 | 5,48 |
| Lamotrigin | Lamotrigin "Teva" TEVA
|
tabletter 25 mg | 56 stk. (blister) | 0,99 | 11,91 |
| Lamotrigin | Lamotrigin "Teva" TEVA
|
tabletter 25 mg | 100 stk. (blister) | 1,51 | 18,10 |
| Lamotrigin | Lamotrigin "Teva" TEVA
|
tabletter 50 mg | 56 stk. (blister) | 1,05 | 6,33 |
| Lamotrigin | Lamotrigin "Teva" TEVA
|
tabletter 50 mg | 100 stk. (blister) | 1,47 | 8,81 |
| Lamotrigin | Lamotrigin "Teva" TEVA
|
tabletter 100 mg | 56 stk. (blister) | 1,98 | 5,93 |
| Lamotrigin | Lamotrigin "Teva" TEVA
|
tabletter 100 mg | 100 stk. (blister) | 2,85 | 8,55 |
| Lamotrigin | Lamotrigin "Teva" TEVA
|
tabletter 200 mg | 56 stk. (blister) | 1,49 | 2,24 |
| Lamotrigin | Lamotrigin "Teva" TEVA
|
tabletter 200 mg | 100 stk. (blister) | 2,02 | 3,03 |
| Lamotrigin | Lanotok Parallelimport
|
tabletter 100 mg | 98 stk. (blister) | 8,10 | 24,31 |
| Lamotrigin | Lanotok Parallelimport
|
tabletter 100 mg | 100 stk. (blister) | 8,14 | 24,42 |
